Diagnostic performance of SD Bioline malaria antigen P.f® for the detection of malaria infections in pregnant women in the third trimester of pregnancy in Burkina Faso

Abstract

Burkina Faso has introduced the RdT at large scale in 2009 to improve the diagnosis and control of
malaria control mainly in peripheral areas with limited resources. we undertook the evaluation of the diagnostic
performance of Sd Bioline malaria antigen Pf® for the diagnosis of malaria in pregnancy in two
health districts of Bobo-dioulasso. From February 2014 to February, 2015 we enrolled 705 women in the
3rd trimester of pregnancy attending the antenatal visits in primary health centers in Bobo-dioulasso. They
were all subjected blood testing for malaria infection using either RdT or microscopy. Together, the
results showed that of the prevalence of malaria among our participants were 5.25% by microscopy and
11.7% by RdT. The sensitivity and the specificity of the RdT were respectively 78.4% of (Ci95 % 62.1 -
88.9) and 91.9 % of (Ci95 % 89.6 - 93.8). also, the calculated positive and negative predictive values
were respectively 34.9% (Ci95 % 25.4 - 45.8) and t 98.7 % Ci95% 97.4 - 99.4).
Together, the study results showed that Sd Bioline malaria antigen P.f® could be a reliable alternative to
the microscopy for malaria diagnosis during pregnancy in Burkina Faso.