Silent circulation of SARS-CoV-2 in Burkina Faso: Seroprevalence data from blood donors two years after the onset of the pandemic in Bobo-Dioulasso

Authors

  • Yi Ye Aburi Andre Nagalo Universite Ledea Bernard Ouédraogo
  • Hayazouma Hadiaratou Inès HAKIEKOU Laboratoire des Pathogènes Émergents et Réémergents (LaPathER), Université Nazi Boni, Bobo-Dioulasso, Burkina Faso
  • Yacouba SAWADOGO Laboratoire des Pathogènes Émergents et Réémergents (LaPathER), Université Nazi Boni, Bobo-Dioulasso, Burkina Faso
  • Merci MUHIGWA Laboratoire des Pathogènes Émergents et Réémergents (LaPathER), Université Nazi Boni, Bobo-Dioulasso, Burkina Faso
  • Dieudonné Odilon KABORE Laboratoire des Pathogènes Émergents et Réémergents (LaPathER), Université Nazi Boni, Bobo-Dioulasso, Burkina Faso
  • Hervé KAFANDO Laboratoire des Pathogènes Émergents et Réémergents (LaPathER), Université Nazi Boni, Bobo-Dioulasso, Burkina Faso
  • Augustin KONKOBO Laboratoire des Pathogènes Émergents et Réémergents (LaPathER), Université Nazi Boni, Bobo-Dioulasso, Burkina Faso
  • Yétéma Dieudonné YONLI Centre Régional de Transfusion Sanguine, Centre National de Transfusion Sanguine, Bobo-Dioulasso, Burkina Faso
  • Téwendé Céline Alice Rosine KOUMARE/KIBA Centre Régional de Transfusion Sanguine, Centre National de Transfusion Sanguine, Bobo-Dioulasso, Burkina Faso
  • Abdoul-Salam OUEDRAOGO Laboratoire des Pathogènes Émergents et Réémergents (LaPathER), Université Nazi Boni, Bobo-Dioulasso, Burkina Faso

DOI:

https://doi.org/10.64707/revstss.v48i2.1993

Keywords:

SARS-CoV-2 ; séroprévalence ; donneurs de sang ; COVID-19 ; Burkina Faso, SARS-CoV-2; seroprevalence; blood donors; COVID-19; Burkina Faso

Abstract

Abstract :

Background: Serological studies are crucial for estimating the true circulation of SARS-CoV-2, particularly in contexts where virological surveillance is limited. This study aimed to assess the seroprevalence of anti-SARS-CoV-2 antibodies among blood donors in Bobo-Dioulasso, two years after the onset of the pandemic.

Methods: A cross-sectional descriptive study was conducted from May 2022 to May 2023 at the Regional Blood Transfusion Center (CRTS) of Bobo-Dioulasso. Serum samples were tested using the ELISA technique (WANTAI SARS-CoV-2 Ab ELISA kit) to detect total antibodies against SARS-CoV-2. Sociodemographic, clinical, and biological data were analyzed using R software version 4.2.1.

Results: A total of 438 donors were included; 82.9% were male, with a median age of 26 years, and 79.5% were unvaccinated against COVID-19. The overall seroprevalence was 98% (95% CI: 95.9–99.2%), reaching 100% among vaccinated donors and 97.99% among unvaccinated donors. No significant differences were observed according to sex, age, education level, or blood group (p > 0.05).

Conclusion: Two years after the onset of the pandemic, almost all blood donors in Bobo-Dioulasso had anti-SARS-CoV-2 antibodies, indicating widespread viral circulation in the asymptomatic population. Integrating serological surveillance into national post-pandemic monitoring strategies would help better assess community immunity and anticipate potential resurgences.

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Published

2025-12-31

How to Cite

Nagalo, Y. Y. A. A., HAKIEKOU , H. H. I., SAWADOGO , Y., MUHIGWA , M., KABORE , D. O., KAFANDO , H., KONKOBO , A., YONLI , Y. D., KOUMARE/KIBA , T. C. A. R., & OUEDRAOGO , A.-S. (2025). Silent circulation of SARS-CoV-2 in Burkina Faso: Seroprevalence data from blood donors two years after the onset of the pandemic in Bobo-Dioulasso. Sciences De La Santé, 48(2), 41–54. https://doi.org/10.64707/revstss.v48i2.1993

Issue

Vol. 48 No. 2 (2025): (2) juillet-décembre

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