Detection of pulmonary tuberculosis and COVID-19 co-infection in the city of Ouagadougou, Burkina Faso

Auteurs

  • Arouna ZOUNGRANA
  • Tani SAGNA
  • Koudbi Jacob ZONGO
  • W. Yasmine Astrid SANA
  • Dinanibè KAMBIRE
  • Tinoaga Léon SAWADOGO
  • Albert SOUDRE
  • Serges SOUGUE
  • Arzouma Paul YOODA
  • Naâ-Imwine Stanislas Dimitri MEDA
  • Kouka Zoéwentallé Thibaut OUEDRAOGO
  • Tegwinde Rebeca COMPAORE
  • Lassina TRAORE
  • Wendkuuni Florencia DJIGMA
  • Ollo YOUL
  • Adjima COMBARY
  • Adama ZIGANI
  • Abdou Azaque ZOURE
  • Absatou KY/BA
  • Amadou TRAORE
  • Henri Gautier OUEDRAOGO
  • Elie KABRE
  • Jacques SIMPORE

Mots-clés :

Co-infection, Tuberculosis;, COVID-19;, Mycobacterium tuberculosis;, SARS-CoV-2;, Burkina Faso.

Résumé

Introduction: Pulmonary tuberculosis and COVID-19 have shared some similarities in term of clinical manifestations and modes of transmission. COVID-19 could increase the mortality rate of tuberculosis. Consequently, pulmonary tuberculosis and COVID-19 co-infection could be a major public health concern. The aim of this study was to establish the prevalence of pulmonary tuberculosis and COVID-19 co-infection in the city of Ouagadougou, Burkina Faso. Method: Mycobacterium tuberculosis DNA, was detected using GeneXpert (Cepheid, USA), on the sputum of suspected pulmonary tuberculosis. Anti-SARS-CoV-2 antibodies (IgM and IgG) was detected using the Accu-Tell rapid kit (AccuBio Techn Co, Ltd kit) on the blood plasma of suspected pulmonary tuberculosis cases. SARS-CoV-2 RNA amplification was then performed using the TaqPath kit (Applied Biosystems), with the QuantStudio 5 thermocycler on nasopharyngeal swabs from patients found positive for pulmonary tuberculosis. Results: The prevalence of pulmonary tuberculosis was 27.54% (65/236). Among tuberculosis-positive patients who accepted the COVID-19 serological test, co-infection was 12.5% (3/24). The prevalence of Mycobacterium tuberculosis resistance to rifampicin was 9.23%. Males and patients aged 40 and below were the most likely to be infected with pulmonary tuberculosis at 76.90% and 66.20% respectively. Seroprevalence of COVID-19 was 12.63%. Conclusion: Pulmonary tuberculosis and COVID-19 co-infection was a reality in this study.

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Publiée

10/19/2024

Comment citer

ZOUNGRANA, A., SAGNA, T. ., ZONGO, K. J. ., SANA, W. Y. A. ., KAMBIRE, D. ., SAWADOGO, T. L., SOUDRE, A. ., SOUGUE, S., YOODA, A. P. ., MEDA, N.-I. S. D., OUEDRAOGO, K. Z. T. ., COMPAORE, T. R. ., TRAORE, L. ., DJIGMA, W. F. ., YOUL, O. ., COMBARY, A. ., ZIGANI, A., ZOURE, A. A. ., KY/BA, A., TRAORE, A. ., OUEDRAOGO, H. G. ., KABRE, E. ., & SIMPORE, J. . (2024). Detection of pulmonary tuberculosis and COVID-19 co-infection in the city of Ouagadougou, Burkina Faso. Sciences De La Santé, 47(1), 152–164. Consulté à l’adresse https://revuesciences-techniquesburkina.org/index.php/sciences_de_la_sante/article/view/1562

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