Detection of pulmonary tuberculosis and COVID-19 co-infection in the city of Ouagadougou, Burkina Faso
Mots-clés :
Co-infection, Tuberculosis;, COVID-19;, Mycobacterium tuberculosis;, SARS-CoV-2;, Burkina Faso.Résumé
Introduction: Pulmonary tuberculosis and COVID-19 have shared some similarities in term of clinical manifestations and modes of transmission. COVID-19 could increase the mortality rate of tuberculosis. Consequently, pulmonary tuberculosis and COVID-19 co-infection could be a major public health concern. The aim of this study was to establish the prevalence of pulmonary tuberculosis and COVID-19 co-infection in the city of Ouagadougou, Burkina Faso. Method: Mycobacterium tuberculosis DNA, was detected using GeneXpert (Cepheid, USA), on the sputum of suspected pulmonary tuberculosis. Anti-SARS-CoV-2 antibodies (IgM and IgG) was detected using the Accu-Tell rapid kit (AccuBio Techn Co, Ltd kit) on the blood plasma of suspected pulmonary tuberculosis cases. SARS-CoV-2 RNA amplification was then performed using the TaqPath kit (Applied Biosystems), with the QuantStudio 5 thermocycler on nasopharyngeal swabs from patients found positive for pulmonary tuberculosis. Results: The prevalence of pulmonary tuberculosis was 27.54% (65/236). Among tuberculosis-positive patients who accepted the COVID-19 serological test, co-infection was 12.5% (3/24). The prevalence of Mycobacterium tuberculosis resistance to rifampicin was 9.23%. Males and patients aged 40 and below were the most likely to be infected with pulmonary tuberculosis at 76.90% and 66.20% respectively. Seroprevalence of COVID-19 was 12.63%. Conclusion: Pulmonary tuberculosis and COVID-19 co-infection was a reality in this study.
Téléchargements
Publiée
Comment citer
Numéro
Rubrique
Licence
(c) Tous droits réservés Sciences de la Santé 2024
Ce travail est disponible sous la licence Creative Commons Attribution 4.0 International .